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br Author contributions br Competing financial
2018-11-06

Author contributions Competing financial interests Acknowledgments We thank Dr. Sravan K. Goparaju for critical reading our manuscript. This work was supported in part by JSPS KAKENHI (23500446) and the iCeMS exploratory grant for junior investigators to KA. TI was supported in part by the
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Interestingly in contrast to the common
2018-11-06

Interestingly, in contrast to the common roles of SNAI-1 and 2 in repressing E-cadherin mediated EMT, SNAI-1 is the only SNAI factor that is expressed in endoderm and Hep cells, and that instructs positively hepatic cell fate. The unique function of SNAI-1 compared to SNAI-2 was also noted during th
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The host immune response has been
2018-11-06

The host immune response has been identified as a critical regulator of tumor development and progression (Dunn et al., 2004; Fridman et al., 2013; Hadrup et al., 2013). Several types of immune 17-aag participate in immunosurveillance by direct killing or production of cytokines. Our expression prof
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Sulfo-NHS-LC-Biotin Prolonged APs and EADs are typical of ph
2018-11-06

Prolonged APs and EADs are typical of pharmacologically induced LQTS modeled in nonhuman hearts (Shimizu and Antzelevitch, 2000; Studenik et al., 2001; Terentyev et al., 2014), yet few such studies examined [Ca2+]i transients. The lengthening of APs and [Ca2+]i transients after pharmacologically blo
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Operationally CTS provides a marked improvement in the effic
2018-11-05

Operationally, CTS provides a marked improvement in the efficiency of isolating precision-modified iPSC lines compared with direct cloning-based methods, without extended hands-on time or a requirement for additional instrumentation. Following methodological refinements and legislating for effect ra
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In both approaches the dynamics of the scale factor of
2018-11-05

In both approaches the dynamics of the scale factor of the universe at the inflation stage was considered as a classical one. However, quantum effects, for instance, the ordinary matter creation, are important at the final stages. This also concerns the dynamics of the scale factor of the universe.
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The results of Poisson regression are shown
2018-11-05

The results of Poisson regression are shown in Table 2 (men) and 3 (women). Age-adjusted PRs (95% CIs) for each outcome by survey year and p-values for temporal trends are presented. Although point estimates varied by year, the associations of SRH and health behavior with SES were observed, with som
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It is well established that work can influence health
2018-11-05

It is well-established that work can influence health and wellbeing in both positive and negative ways (Ross & Mirowsky, 1995; LaMontagne & Keegel, 2009; van der Noordt, IJzelenberg, Droomers, & Proper, 2014). There also evidence that persons with disability have poorer health and wellbeing compared
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I examine the association between violence and
2018-11-05

I examine the association between violence and parenting, a key human capital investment. Results show little evidence that parents respond to the negative effects of violence on children by providing more nurturing care. In fact, I find that parental responses become harsher as violence increases (
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Introduction Raw water in South Africa is considered
2018-11-05

Introduction Raw water in South Africa is considered a strategic national resource, with the responsibility for its management taking place at three tiers. These are firstly Central Government, secondly Provincial and Regional Governments, including other specified authorities, and thirdly Local Au
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br Experiments The MgMn Cr O
2018-11-05

Experiments The (MgMn)Cr2O4Spss, with x = 0.00 (0), 0.20 (0), 0.44 (2), 0.61 (2), 0.77 (2) and 1.00 (0), were synthesized in an open air at 1200 °C for 48 h by using a conventional muffle furnace (Wang et al., 2012). Their compositional and powder X-ray diffraction (XRD) data suggested that they
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Wang and associates performed a genetic
2018-11-05

Wang and associates performed a genetic association study of variants and COPD in a southern Chinese population (). They investigated two polymorphisms in the 3′ untranslated region of the gene. The 3′ untranslated region of an mRNA molecule is the sequence following the termination codon and play
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Gut Microbiome and Inflammatory Bowel Disease
2018-11-05

Gut Microbiome and Inflammatory Bowel Disease Modulation of Gut Microbiota in Obesity and Cardiometabolic Disorders Changes in gut microbiota are associated with metabolic disorders such as obesity, type 2 diabetes and cardiovascular risk factors. Patrice D. Cani (Brussels, Belgium), Willem M. d
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In their manuscript in Psomas
2018-11-05

In their manuscript in , Psomas and colleagues used a combination of 68 markers of immune activation and inflammation and two independent hierarchical clustering analyses to identify 5 donor groups from among 120 HIV-infected virologic responders (). These donor groups were characterized using combi
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Stratifying patients according to the toxicity risk and
2018-11-05

Stratifying patients according to the toxicity risk and modulating EBRT dose would provide a valuable tool for personalized EBRT (). Many efforts have been made to develop assays capable of predicting susceptibility for the development of radiation injury that finally allow customization of EBRT pro
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