• br S Nitrosoglutathione reductase GSNOR also identified as

  2022-05-12

  

  S-Nitrosoglutathione reductase (GSNOR) also identified as glutathione-dependent formaldehyde dehydrogenase (FDH), is a zinc-dependent dehydrogenase. It is a member of the alcohol dehydrogenase (ADH) family and is called class III alcohol dehydrogenase that regulates the levels of S-nitrosothiols (

• GPR belongs to the G protein

  2022-05-11

  

  GPR84 belongs to the G protein-coupled receptor family, and it was first identified from human peripheral blood neutrophils [,]. GPR84 is now considered to be a member of receptor for medium chain fatty Deacetylase Inhibitor Cocktail (MCFA) with carbon chain lengths of 9–14 []. GPR84 is mainly expr

• Histamine functions as a key neurotransmitter in multiple ci

  2022-05-11

  

  Histamine functions as a key neurotransmitter in multiple circuits to control various behaviors. In Drosophila photoreceptor, e-mail is produced de novo by histidine decarboxylase (Burg et al., 1993); meanwhile, maintaining normal histamine content also depends on the histamine recycling pathway (Bo

• Introduction Histamine was generally accepted

  2022-05-11

  

  Introduction Histamine was generally accepted as a neurotransmitter in 1984, when histamine was first identified to be located in tuberomamillary nucleus (TM) of the brain (Watanabe et al., 1984). In mammals, histaminergic neurons play an important role in regulating multiple physiological activiti

• Polydatin receptor Assuming thus a positive signal for both

  2022-05-11

  

  Assuming thus a positive signal for both GLUT1 and GLUT3 in our conditions, a more detailed explanation of the results observed through immunocytochemistry is needed. In this way, it must be reminded that syncytiotrophoblasts compose the outer layer of the trophoblast, are in direct contact with mat

• A main finding of this study was that

  2022-05-11

  

  A main finding of this study was that the impact of exogenous insulin on hippocampal memory and glucose utilization was GluT4-dependent. Although insulin was administered directly to the hippocampus, it is important to point out that such administration does indeed have physiological relevance; that

• br Acknowledgements We thank the

  2022-05-11

  

  Acknowledgements We thank the following individuals for notable contributions to this work: Dr. Ruth Wood, Dr. Alan Watts, Dr. Casey Donovan, Andrea Suarez, Emily Nakamoto, Allison Apfel, April Banayan, and Jonathan Cheung. This study was supported by the National Institute of Health grants, DK10

• In addition to our results Chen et al showed

  2022-05-11

  

  In addition to our results, Chen et al. showed that administration of the GalR1 antagonist M40 improves cardiac function and attenuates cardiac remodeling in rats with heart failure [26]. These effects might be attributed to M40 suppression of galanin inhibitory effect on the vagal nerve in heart fa

• br Declaration of interest br Acknowledgments br This work

  2022-05-11

  

  Declaration of interest Acknowledgments This work was supported by grants from the Polish National Science Centre (PRELUDIUM grant no. 2013/11/N/NZ5/00270) and the European Commission FP7 Project Beta-JUDO (grant number 279 153), European Union EIT Health project DeTecT2D, Swedish Diabetes A

• The central event eliciting insulin secretion

  2022-05-11

  

  The central event eliciting insulin secretion is the production of ATP which leads to the inhibition of ATP-sensitive inwardly-rectifying K+ATP channels, a consecutive depolarization of the plasma membrane with opening of voltage-dependent Ca2+ channels and Ca2+ influx into the beta-cell. However, i

• salicin The observed tendency for higher plasma lactate

  2022-05-10

  

  The observed tendency for higher plasma lactate levels in the aerated thermal exposure suggests increased reliance on salicin metabolism to maintain function. This finding is supported by a recent study that observed an increased ṀO2 in European perch (Perca fluviatilis) exposed to a hyperoxic rathe

• The mode of action of m Tyr has

  2022-05-10

  

  The mode of action of m-Tyr has not been fully recognized. The primary/basic mechanism of action of m-Tyr is thought to be associated with the incorporation of this NPAA into the structure of proteins resulting in formation of dysfunctional proteins [11], [12]. m-Tyr is incorporated into proteins in

• G protein coupled receptors GPCRs

  2022-05-10

  

  G-protein coupled receptors (GPCRs) constitute a large family of 7 trans-membrane-spanning proteins that activate internal signal transduction cascades through binding to different ligands including neurotransmitters, peptides, and lipids [7]. This family of receptors has therapeutic potentials in t

• Treatment with probiotics can also be used to alter the

  2022-05-10

  

  Treatment with probiotics can also be used to alter the microbiota profile of CF patients. One study reports that administration of the probiotic Lactobacillus Reuteri improved digestive health and inflammation [112]. The fecal microbial profile changed, showing a decrease in Proteobacteria and an i

• So far GnRH receptors have been detected in the

  2022-05-10

  

  So far, GnRH receptors have been detected in the human ovary, but their physiological importance is still unclear (). In particular, GnRH receptors as well as GnRH types I and II have been localized in the granulosa bromodomain inhibitor of pre-ovulatory follicles, but not of follicles from the pri

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